Night Blindness and Diabetes in a Non-Caucasian Cystic Fibrosis Patient in Iran
نویسندگان
چکیده
Cystic fibrosis (CF) is an autosomal recessive lethal disease that is predominantly occur in the caucasian populations and causes many clinical signs. The major clinical signs are pancreatic insufficiency and progressive lung disease but night blindness and diabetes are less well known. We report a fifteen years old non-caucasian girl that have cystic fibrosis with atypical night blindness, diabetes and nasal polyps symptoms in addition to some of major clinical symptoms. Molecular analysis of this patients showed that she was homozygote for 1677delA mutation. Clinical signs in CF are vast and related to organs which are affected. patients may present typical or atypical conditions. with progress in the management of cystic fibrosis and improvement in life expentancy, several atypical symptoms are expected to emerge. So it is important to screen patients for possible co-morbidities.
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